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doi: 10.1078/0171-9335-00193

10.1111/j.1476-5381.2011.01480.x Br J Pharmacol

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Results indicate that the methylation frequencies of SIRT3, SMARCA5, and CDH1 do not differ significantly among young individuals, elderly individuals, and AD patients, suggesting that methylation of these genes is not related to aging or AD (63)

Unlike the Phoqus formulation, which appeared to transit the gastrointestinal (GI) tract slower and more predictably than multi-particulates, the rapid transit of the multi-particulates we presumed had resulted in the majority of the drug payload being delivered to the colon, a region of the GI tract wherein the absorption of hydrocortisone had not been formally studied