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Additionally, we proposed that an ACO participating in Levels C-E of the BASIC track or the ENHANCED track may not use any prepaid shared savings to pay back any shared losses that it would have incurred as specified in a written notice from CMS under 425.605(e)(2) or 425.610(h)(2), respectively

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Deducing from these results, the mechanism of ICT action might not solely be the iron-deprivation but rather also a modulation of ROS homeostasis and intracellular signaling

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