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Curr Med Chem 19(23):4000

Nearly 50% of the cases are attributed to chromosomal aberrations, nevertheless, there is further evidence linking substantially higher rates of miscarriage to factors involving ethnic origin, the mother's psychological state, extremely high or low BMI pre-pregnancy, stress, smoking, use of non-steroidal anti-inflammatory drugs, and alcohol consumption

Importantly, the overexpression of Parkin significantly protected SH-SY5Y cells from AIMP2-induced cell death

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A saponin associated with antioxidant activity against ALS is Madecassoside (Fig