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[Updated 2019 May 4]

Aerotolerance and peroxide resistance in peroxidase and PerR mutants of streptococcus pyogenes

Finally, a mutant defective for both glycerol and hexose phosphate utilization ( glpD / golD/ uhpT ) phenocopied a hexose phosphate mutant ( uhpT ) alone suggesting no additive role for glycerol in the context of multicycle infection and cell to cell spread in fibroblasts (Fig 2B)

Nevertheless, additional clinical trials are required to establish appropriate dosages, evaluate long-term safety, and validate their therapeutic efficacy during pregnancy

Nature 593 , 282-8 (2021)

43 Pathological cardiac hypertrophy is commonly associated with diverse etiologies such as hypertension, arterial stenosis, myocardial infarction, and dilated cardiomyopathy, which progressively leads to cardiac remodeling and heart failure