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doi: 10.1007/s00726-016-2254-8 59 AffaticatiPMignenOJambouFPotierMCKlingel-SchmittIDegrouardJet al

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These findings suggest that pharmacological inhibition of FSP1 may provide an effective strategy for cancer therapy by sensitizing cancer cells to ferroptosis-inducing chemotherapeutic drugs and, if used in combination with GPX4 inhibitors, could have a strong synergistic effect