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Journal of Agricultural and Food Chemistry, 73 (11), 63856399

For instance, Curcumin has been shown to covalently bind to the Cys151 residue of KEAP1, thereby stabilizing NRF2 and enhancing antioxidant effects

The acquired resistance aligned with decreases in cell proliferation and in the extent of lipid peroxidation, as well as with an increase in the expression of GPX4 upon differentiation

60 Deletion of the AdipoR1 gene leads to obesity caused by lower energy expenditure, whereas deletion of the AdipoR2 gene leads to higher energy expenditure and a lean phenotype

Acknowledgements The authors thank Conselho Nacional de Pesquisa e Tecnologia (CNPq) and Fundao de Amparo Pesquisa do Estado de So Paulo (FAPESP)

(2005) A multicenter phase II trial of ZD6474, a vascular endothelial growth factor receptor-2 and epidermal growth factor receptor tyrosine kinase inhibitor, in patients with previously treated metastatic breast cancer