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doi: 10.1200/jco.2004.99.245 15 BarnesJ

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Rotating shift work, which disrupts circadian rhythms, has also been associated with a 4% increased risk for ischemic stroke for every 5 years, with an increased risk of stroke in women with longer durations of shift work ( 15 years) (Brown et al., 2009)

A: Keep the bottle in a cool and dry place, away from direct sunlight, to maintain the tablets' resplendent efficacy over 24 months from the manufacturing date