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This protein can create an iron-overloaded environment and lay the foundation for the occurrence of cellular ferroptosis

All searched spectra were imported into Scaffold (v5.3, Proteome Software) and scoring thresholds were set to achieve a peptide false discovery rate of 1% using the PeptideProphet algorithm

FIGURE 2 Worthy of mention is that nuclear receptor coactivator 4 (NCOA4) can promote iron storage or release from ferritin and plays a crucial function in maintaining a dynamic balance of intracellular iron

Naloxone creates an increase in oxygen saturation in excess of the increase in ventilation, so better ventilation-perfusion matching is established in the acute illnesses with acute respiratory failure [84]

469 The mitochondrial protein sideroflexin 1 (SFXN1) is responsible for importing iron from the cytoplasm to the mitochondria, and SFXN1 deficiency leads to mitochondrial respiratory chain damage, affecting the biogenesis and assembly of complex III