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PMCID: PMC9927842 Onyeakazi UM, Columb MO, Rosalind A, Kanakarajan S, Galley HF (2024) Melatonin treatment has consistent but transient beneficial effects on sleep measures and pain in patients with severe chronic pain: the DREAM-CP randomised controlled trial

In preclinical adipocyte models, studies suggest this shift in metabolic flux is associated with changes in lipogenic gene expression, including reduced expression of key adipogenic transcription factors