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A lower Firmicutes/Bacteroidetes ratio (142), reduced counts of Lactobacillaceae (143), and altered abundance of several genera have been reported (144) including Eggerthella , Klebsiella , Flavonifractor , Lachnospiraceae (145, 146), Prevotella , Eubacterium, and Rhodococcus were significantly enriched, whereas Pseudobutyrivibrio and Dialister were decreased in SLE patients (147)

BrSM is rooted in the idea that robust and effective solutions for complex diseases should optimize an individuals homeostatic and allostatic systems and their interactions across all biological systems and emerges in part as a response to the limitations of the reductionist perspective model [531]

Manganese superoxide dismutase and glutathione peroxidase as prognostic markers in patients with buccal mucosal squamous cell carcinomas

doi: 10.1126/science.124.3220.484-a

A single layer of IECs covered by abundant mucus comprise the epithelial portion of the gut barrier, while ECs constitute the vascular component (Thomas, 2016)

and Smith, J.D