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Acknowledgements The study is supported by a Singapore EDB-IPP grant (grant number: RL2012035)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 48.Sensenbrenner M, Jaros GG, Moonen G, Meyer BJ

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This prolonged exposure does not proportionally increase therapeutic benefit because tissue binding sites saturate, but it does increase total copper exposure