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There is accumulating evidence for diverse changes in molecular expression of reactive astrocytes in different types and different severities of tissue pathology, 62,65,68,69 but there is not yet a good synthesis of how molecular, metabolic, 87 structural, and functional changes relate to one another to generate precisely definable phenotypes

By delineating the relationship between the key inflammatory mediator GSDMD in SCs and oxidative damage in HCs, we defined an underlying intercellular signaling circuit in NIHL

This observation suggests that the microbial community compositions of the PMA+ samples from the NT group and the PMA- samples across all groups are largely similar, whereas the microbial community compositions of Glut and THPS PMA+ samples differed more from each other and from the rest of samples, as also indicated by the Jaccard distances

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doi: 10.1016/j.phymed.2022.154411 102 WeiRZhaoYWangJYangXLiSWangYet al