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Excitotoxicity may occur when, for instance, extracellular glutamate accumulates due to impaired uptake by astrocytes or excessive synaptic release

Skin infections are eliminated by cooperation of the fibrinolytic and innate immune systems

Additionally, reduced expression of glial fibrillary acidic protein (GFAP) and lonized calcium-binding adapter molecule 1 (Iba-1) in glial cells was observed, indicating decreased inflammatory responses

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With few exceptions (see below), generation of the radical intermediate, and therefore the reduction of ribonucleosides, is driven by electrons provided through a dithiol-disulfide exchange

C3 protein is cleaved and activated by C3-convertase to C3a and C3b in the complement system 4 ) and apoptosis 5