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Subcutaneous administration of zoledronic acid to rabbits during organogenesis did not cause adverse fetal effects at up to 0.4 times the human 5 mg intravenous dose (based on body surface area, mg/m2), but resulted in maternal mortality and abortion associated with hypocalcemia starting at doses equivalent to 0.04 times the human 5 mg intravenous dose

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The cucumber leaves were sampled after treatment at 0, 3, 12, and 24 h, frozen immediately in liquid nitrogen, and stored at 80C until further analysis

Many NSAIDs (non-steroidal anti-inflammatory drugs) that are used for mild pain relief are actually not especially safe to take on a daily basis

Potential Benefits Wound healing (preclinical): Animal studies report faster wound healing and tissue repair via enhanced angiogenesis and cell migration [5] [6]