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Despite the rarity of each individual condition, rare diseases collectively affect over 400 million people worldwide 1 approximately eight times the global number of cancer patients 2

doi: 10.3390/molecules21050559

[2] Finasteride Finasteride is contraindicated in pregnant women as it may cause harm to the unborn child

From these metrics, participants were stratified into four clinical groups: neuropathological AD diagnosis with dementia (dementia, 25 participants), neuropathological AD diagnosis without dementia (resilient, 25 participants), no AD or other neurological disease diagnosis with dementia (frail, 26 participants), and a control group with no AD or other neurological disease diagnosis and negligible cognitive decline at time of death (control, 26 participants)

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