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We found strong negative correlations between lipid peroxidation, mitochondrial superoxide and inflammasome activation and the frequency of CD14 low CD16 + monocytes and also CCR2 expression on CD14 high CD16 monocytes ( Figure 5A )

Filipek PA, Juranek J, Nguyen MT, Cummings C, Gargus JJ

Nature 2008;452:10126

Sepsis alters the megakaryocyteplatelet transcriptional axis resulting in granzyme Bmediated lymphotoxicity