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At temperatures colder than 25 C, denatured RuBisCO had similar active site density (4.8 10 3 INPs mg 1 ) as native RuBisCO at 8.8 C (4.6 10 3 INPs mg 1 ) (Fig

Patients should be encouraged to consume B12-rich foods, including: Meat, particularly liver and kidney Fish and shellfish Dairy products (milk, cheese, yoghurt) Eggs Fortified breakfast cereals and plant-based milk alternatives For patients following plant-based diets, fortified foods and supplementation become essential, as vitamin B12 is naturally found almost exclusively in animal products

The authors also reported that mouse embryonic fibroblasts of PAD4 knockout mice showed increased FUS aggregation and sequestration into SGs compared with PAD4 overexpression cells, indicating that citrullination inhibits FUS phase separation 113

A., Liu, A

Deficiency leads to nerve damage (neuropathy), which presents as numbness, tingling, or weakness

38 The release of lysosomal enzymes into the cytosol is dependent on the specific lysosomal enzyme cathepsin B