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Chemotherapy can reduce the expression of glucose transporters and impair glucose uptake in cancer cells

Consider the tick-borne Lyme disease, caused by the Borrelia burgdorferi bacteria, which sometimes manifests itself in bullseye pattern skin lesions, but can later progress to muscle dysfunction, arthritis, facial palsy, and more

Pyridoxine antagonists such as isoniazid, cycloserine, penicillamine, and hydralazine may decrease the efficacy of pyridoxine

Mutations in the gene coding for the protein superoxide dismutase 1 (SOD1) were among the first identified as being involved in ALS

Wilmer MJ, Emma F, Levtchenko EN (2010) The pathogenesis of cystinosis: mechanisms beyond cystine accumulation

They have been shown to redistribute heavy metals from other tissues to the brain, increasing brain neurotoxicity and leading to the loss of essential metals, such as zinc, or even hepatotoxicity due to serious side effects due to hepatotoxicity (134)