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Pharmaceutical fentanyl is prescribed to manage severe pain or for emergency sedation

Alcohol decreases inhibitions and judgment and can lead to reckless decisions

It promotes lipolysis, reduces adipogenesis, and improves cellular energy balance

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Clinical trials involving positron emission tomography (PET) with translocator protein expressed by activated microglia (TSPO) have demonstrated that seizures, temporal lobe epilepsy, frontal lobe epilepsy, and focal cortical dysplasia are associated with neuroinflammation, and their acute onset leads to chronic neuroinflammation and exacerbates its deterioration (145)