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doi: 10.1089/neu.2006.0242 69 GuicciardiMLeistMGoresG

353 In PASMCs from MCT-PAH rat models, HMGB1 triggers ERK1/2 signaling, leading to Drp1 phosphorylation and mitochondrial fragmentation, which promotes autophagy activation, resulting in BMPR2 degradation, ID1 downregulation, and PASMC proliferation/migration

Plasma B-vitamins and one-carbon metabolites and the risk of breast cancer in younger women

Proceedings of the National Academy of Sciences, 117(27), 1574015747

For EV cargo to function, two critical steps are required: (1) binding of EVs to recipient cells and (2) intracellular release of the cargo