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Intriguingly, supplementation with mitochondria-targeted TEMPO (mitoTEMPO), which accumulates in active mitochondria where the reduction of its active nitroxide to hydroxylamine is mainly mediated by ubiquinol 35 , also significantly rescued survival upon LDHB silencing (Fig

Zhang, Haoyu

4.1.3 In vitro human studies In vitro studies focus mainly on the antioxidant activity of melatonin and its relationship with the production of gonads