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Being a peptide, it is amphoteric and is metabolized extensively to release its constituent amino acids and methanol.3 Upon ingestion, this artificial sweetener is immediately absorbed from the lumen and metabolized by gut esterases and peptidases to phenylalanine, aspartic acid and methanol

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Stomach issues

The answer depends on three major factors: The specific peptide used The dosage and administration method Medical supervision Many peptides have been safely used in medicine for decades

Ltd.), and protein concentration was measured using the Pierce BCA protein assay (Thermo Scientific)

The degradation can lead to oxidative or reductive changes in amino acid side chains or interactions with formulation excipients, potentially generating immunogenic breakdown products