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Description

The dimer interface, which encompasses the inter-domain linker amino acids (K122, D123, Y124, I125, R126, and N127) is referred to as the hinge region (Gherardi et al., 2006

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It has also been stated that Cbl, along with other B complex vitamins, positively affects the immune system, and deficiencies in these vitamins can decrease immune responses and T-cell proliferation [54,55,56]