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Relative metabolic ratios determined from untargeted metabolomics show that the total ATP/AMP ratio was only altered in ACT-treated WT, suggesting catabolic energy status alteration, whilst in response to ACT, the NAD/NADH ratio was increased in the treated ATP6AP1 KO and GSH/GSSG or ATP/ADP remained comparable in untreated versus treated cells (Fig

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Regulation of BDNF transcription by Nrf2 and MeCP2 ameliorates MPTP-induced neurotoxicity

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