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Available from: Dibbern DA, Montanaro A

[4] Regulation by phosphorylation/dephosphorylation Unlike prokaryotes, in mammals the activity of the pyruvate dehydrogenase complex is also regulated by covalent modifications , namely, the phosphorylation and dephosphorylation of three specific serine residues on the -subunit of pyruvate dehydrogenase, the enzyme that catalyzes the first and irreversible step of the overall reaction sequence

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Each bottle contains 60 capsules, offering a convenient and consistent option for controlled research use