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These findings are of great concern as 24-30% of all pregnant women reported using non-nutritive sweeteners or diet soda during pregnancy

However, in the only randomized, placebo-controlled pilot study to date examining fecal microbiota transplantation in 11 patients with ME/CFSwhere 5 patients received transplants from a universal donor and 6 underwent autologous fecal microbiota transplantation through colonoscopythere were no notable differences in health-related quality of life metrics between the treatment and placebo groups at both 1- and 6-months post-treatment [163]

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The catabolism of methionine is performed by trans-sulfuration, with Hcy reacting with serine to form cystathionine in an irreversible reaction catalysed by cystathione--synthase