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To exclude potential kinetic differences in the ability of DA to recruit -arrestin2 versus G i1 , time-course experiments showed that receptor stimulation by DA does not result in the recruitment of -arrestin2 at any of the time points tested (data not shown)

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Garca-Casares N, Gonzlez-Gonzlez G, de la Cruz-Cosme C, et al

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However, the same degree of beneficial effects has not been observed in humans