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CCM identifies nerve damage before symptoms or electrophysiological abnormalities appear [45, 46]

Prevalence and risk factors associated with prehypertension by gender and age in a Korean population in the KNHANES 2010-2012

10.1016/j.carbpol.2016.12.068 45 LebeaupinC.ValleD.HazariY.HetzC.ChevetE.Bailly-MaitreB

Comparison of GT2 domains with and without donor substrates highlighted a conformational rearrangement of the otherwise flexible C-terminus of the domain for residues 562580, wrapping around the donor substrate binding cavity and positioning the backbone carbonyl of residue Ser569 and Thr571 in a productive conformation for hydrogen bonding with both phosphates of the UDP donor substrate (Fig