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In the context of the association between neuroinflammatory conditions and metabolic syndrome/type II diabetes (in which glutamate may pay a key role) , Stanford researchers (Winer et al, 2011) have demonstrated the effectiveness of Rituximab treatment in mice in an autoimmune model of type II diabetes : B cell effects on glucose metabolism are mechanistically linked to the activation of proinflammatory macrophages and T cells and to the production of pathogenic IgG antibodies

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Long-term side effects including blepharitis leading to discontinuation of ripasudil

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