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specifically, (AEEA)-(-Glu)-(C20 diacid) (where AEEA is 2-[2-(2-aminoethoxy)ethoxy]acetic acid, commonly used as a spacer group in synthetic peptides)

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This will require more precisely targeting the neurobiological mechanisms that underpin reward processes involved in MUD as well as the lasting neurobiological adaptations and neurotoxic changes that can develop with long-term use

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