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Treatment of osteoarthritis with incretin hormones or analogues thereof

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As indicated, in the small intestine, oligopeptides resulting from proteins that were degraded by gastric and pancreatic enzymes (pepsins and proteases) are subsequently digested by peptidases in the brush border of the intestinal wall, and free amino acids are further transported into intestinal cells, follow an intracellular circuit, exported though the basolateral membrane, and canalized into the blood circulation (77, 78)

This may contribute to the emergence of atherothrombotic complications in such patients (185)

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En clearancestudie med enzymimmunoassay mtte intravensa halveringstider p cirka 4,0 minuter hos hund, 2,9 minuter hos apa och 2,0 minuter hos rtta, med en metabolisk clearancehastighet p runt 30,7 ml/kg/min hos hund (PMID 6379493)