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and PPAR-beta/delta, which has multiple pleiotropic effects [22]

Mol Med (Cambridge Mass) (2022) 28(1):117

doi: 10.1159/000491604 27 MaesMMeltzerHYScharpSBosmansESuyEDe MeesterIet al

36 , e22637 (2022)

Ito et al., 2023) (this may be particularly relevant for the destabilization of myelin), synaptic dysfunction (Tu et al., 2014) (this includes impairment of signaling at the axo-myelinic synapse, crucial for survival of the myelinated axon

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