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Specifically, Coppieters et al

This included a transient hyperactive state in excitatory neurons that preceded their loss, validated by acute slice electrophysiology

A key observation is the disruption of cellular homeostasis, often coinciding with disease progression

ROS-dependent signal transduction

Obesity-induced protein carbonylation in murine adipose tissue regulates the DNA-binding domain of nuclear zinc finger proteins

Clearance of eryptotic cells Multicellular organisms lose cells by different genetically controlled processes, leading to cell death, such as apoptosis and necroptosis