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The incidence of Cushings syndrome, either exogenously generated due to prolonged use of glucocorticoid therapy or due to endogenous overexpression due to adrenal tumors, is very low and reported to be at approximately 0.7 to 2.4 individuals per million in the general population (Newell-Price et al., 2006)

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In USA: Gantrex Inc.12 Barr Road 2000 Oxford Drive, Suite 400Ajax, ON L1S 3X9 Bethel Park, PA 1510224 - Hour Emergency Telephone #: CANUTEC (613) 996-6666SECTION 02 - COMPOSITION/INFORMATION on INGREDIENTSOSHA ACGIHIngredients CAS # % (weight) PEL TLVTriethylenetetramine 112-24-3 40-70 n/a n/aTetraethylene Pentamine 112-57-2 3-7 n/a n/aBisphenol A 80-05-7 1-5 0.5 ppm n/aDiethylene Triamine 111-40-0 1-5 10 ppm (skin) 1 ppm TWA (skin)ROUTE OF ENTRY:EYE CONTACT:SKIN CONTACT:SECTION 03 - HAZARDS IDENTIFICATIONMay cause severe irritation with corneal injury which may result in permanentimpairment of vision, even blindness.Short single exposure may result in severe skin burns.Material can cause an allergic skin reaction in humans.A single prolonged exposure may result in material being absorbed in harmfulamounts.INHALATION (ACUTE): May cause respiratory sensitization in susceptible individuals.Excessive exposure may cause irritation to upper respiratory tract.INGESTION:CHRONIC EXPOSURE:Single oral dose toxicity is low

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10.1016/j.vaccine.2016.05.004 73