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Gut microbial metabolite facilitates colorectal cancer development via ferroptosis inhibition

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AGE formation occurs during oxidative stress or hyperglycemia, resulting in the conversion of reversible Schiff-base intermediates to covalently bound Amadori products, which subsequently undergo further chemical rearrangements, resulting in the formation of an irreversibly bound AGE 48

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10.14348/molcells.2019.0003 59 LeiP.HuY.GaoP.DingQ.YanJ.ZhaoJ.et al (2022)

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