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The GPx1 active site has the sequence LUG, where U is the catalytic selenocysteine

[DOI] [PMC free article] [PubMed] [Google Scholar] 80.Gasparetti C, Biochemical and structural characterisation of the copper containing oxidoreductases catechol oxidase, tyrosinase, and laccase from ascomycete fungi

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Rajizadeh MA, Bejeshk MA, Doustimotlagh AH, Najafipour H, Eftekhari M, Mahmoodi M, Azizi M, Rostamabadi F, Pourghadamyari H

Vit C has been demonstrated to attenuate sepsis-induced damage by enhancing the immune response, improving vasopressor synthesis, and reducing endothelial injury, findings that have been observed in clinical settings 19

When given by licensed clinical staff in a clinical setting, IV glutathione has a well-established safety profile