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In agreement with KYN and NO level plasma lactate is significantly elevated in the OVX animals compared to control and this was reversed by E2 administration, further indicating systemic inflammation induced by estrogen-deprivation and its mitigation in presence of estrogen (Figs

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As a commonly used clinic chemotherapeutic agent, cisplatin resistance in cancer is associated with the decreased intracellular drug accumulation, and the enhanced DNA repair capacity along with dysregulation of ferroptosis-related signaling pathways

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Using xenon as a probe for dioxygen-binding sites in copper amine oxidases