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As delirium duration predicts long-term cognitive decline after critical illness, these findings support a model in which delirium propagates neuronal injury, thereby contributing to post-ICU cognitive impairment

JACC Basic Transl Sci 3(4):503517

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Fecal matter from metformin-treated mice attenuates intestinal ferroptosis induced by IIRI To investigate the role of the gut microbiota in the anti-ferroptosis effect of metformin, we established a dirty cage group by allowing mice to feed on metformin-modulated feces from the MET group

Haque R, Shamsuzzama, Kumar L, Sharma T, Fatima S, Jadiya P et al (2020) Human insulin modulates -synuclein aggregation via DAF-2/DAF-16 signalling pathway by antagonising DAF-2 receptor in C