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Description

Oxidative modification to tyrosine can occur in one of two ways: a hydrogen atom in the 3 position of a tyrosine ring can be replaced with a nitro-group (3-Nitro-Tyrosine (3NT)), or tyrosines can react with each other to form 3,3-dityrosine crosslinks

Y.KorzhV.et al

For example, spermidine/spermine N1-acetyltransferase 1 ( SAT1 ), a tumor protein p53 (TP53) target gene, mediates the expression of ALOX15 (but not ALOX5 and ALOX12) and is involved in TP53-mediated ferroptosis in H1299 cells