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Pre-analytical oxidation can distort GSH and GSSG results
Oxidative stress is continually produced and continually present in the human body
It is difficult to judge for sure whether the early drastic decrease in Plp- and Mog- positive cells implies a drastic death/loss of the mature OLs or just an extreme-down regulation of the expression of these myelin-associated genes by the OLs while they themselves are still alive
Readers may well remember that a few years ago a similar thing happened at a Health Centre in Dorset which we became involved in
Methods: Retrospective analysis using the 2020 National Inpatient Sample dataset, and utilizing relevant ICD-10-CM codes to calculate the adjusted odds ratio (AOR)
