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The proteins elute in order of their hydrophobicity

doi: 10.1177/0394632015627281 [DOI] [PMC free article] [PubMed] [Google Scholar] 91

Furthermore, NF-B modulates p53-mediated apoptosis via promoting the polyubiquitylation and degradation of p53

2010;298(6):R1475-R1484

B12 B12 is an essential vitamin that is required for protein synthesis, cell reproduction, and normal growth

Developing cell-type-specific SIRT1 regulatorsfor example, hepatocyte-targeted molecules using GalNAc ligands or KC-specific nanoparticlesmay allow targeted activation, while selective inhibition in cells such as activated HSCs could also be explored