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J Alzheimers Dis 20(s2):S609S631 Mar M et al (2020) Mitochondrial glutathione: recent insights and role in disease

207 In the entorhinal cortex and hippocampus of AD patients, high-molecular-weight DNA fragmentation and altered nuclear morphology suggest increased apoptosis

During the early stages of PD, [11C]BU99008 PET showed an increased uptake in frontal, temporal, parietal, occipital and insula cortices and subcortical regions such as caudate, putamen, thalamus and brainstem as compared with healthy controls, whereas in advanced stages these differences disappeared 365