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doi: 10.1111/ejn.v53.12 52 ReayWRCairnsMJ

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2.2.2 Individual differences and inheritance It is estimated that 11.6 out of every 100,000 Chinese suffer from UC, according to a large number of statistical studies, especially in the southeastern coastal areas with Westernized lifestyles, North America and Europe have higher rates of UC than Asia, with 156 to 291 cases per 100,000 people (27)

The increase in lactate that we detected points towards a defect in oxidative energy metabolism, but this conclusion must be treated cautiously given the difficulty of measuring lactate in the presence of the much larger and broader macromolecule (MM) resonance at ~1.35 ppm, with the lactate signal being a small shoulder on that peak (Fig

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