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Description

On the other hand, the structure of the second conformer aqII is stabilized by two hydrogen interactions: between the Dtryptophan's carbonyl group and the terminal NH 2

Its core actions involve: (1) Direct binding to the catalytic domain of matrix MMP-9(Kd = 8.4 nM) and active sites of MMP-1/3, with Ce6-diPEG-curcumin conjugates (200 nM) combined with photodynamic therapy reducing UVB-induced MMP-2 expression by 67% (Thapa Magar et al., 2023