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HMOX activity was determined by measurements of CO production using gas chromatography with a reduction gas analyzer (Peak Instruments, Menlo Park, CA, USA) as described previously.21 HMOX activity was calculated as pmol CO/h/mg of protein

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O 2 .- levels in the cell lysate were determined by WST-1 assay

Both L-citrulline and L-citrulline malate can raise levels of L-citrulline in the body, but there are several reasons why we prefer the L-citrulline form

Mitochondrial sirtuin 3: new emerging biological function and therapeutic target

Glucose metabolism disruptions occur not only in pathology but also with aging, marked by metabolic abnormalities and bioenergetic dysregulation [72]