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The study has been performed in accordance with the principles of Declaration of Helsinki

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Besides clinical applications, further toxicological investigations would also help to understand if the thiomethyl shunt acts only as a pathway for NAPQI detoxification and excretion, or if it can contribute to liver or renal toxicity in case of APAP overdose through the generation of intermediates with highly reactive sulfur-containing fragment as observed with environmental contaminants ( e.g

Type 2 diabetes: sensitization, not just weight Diabetes trials measure a different baseline and endpoint than obesity trials

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