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Mult Scler 24:3235

High K + -induced depolarization amplifies neuroprotection provided by UA through a mechanism involving Ca 2 elevation and extracellular signal-regulated kinases (ERK 1/2 ) activation ( Figure 3 )

The amount of cysteine or cysteamine released was determined by adding 1 mM BrP forming cyclic sulfur products (lanthionine ketimine and aminoethylcysteine ketimine) that absorb at 296 nm ( = 6200 M 1 cm 1 ), while after adding NaOH (20 mM final concentration) to the solution the homocysteine released was determined by the reaction with 1 mM BrP

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It is also crucial to note that astrocytes express NE transporter (NETT) and 5-HT transporter (SERT), which are the targets of some traditional antidepressants

Read counts were summarized to the gene level using the tximport R package 124