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Ubiquinone activity is required for sustaining amino acid pools To directly test whether ubiquinone supports amino acid biosynthesis, we used complementary approaches to inhibit its production independently of statins

Antibiotic mixture administered in NOD/ShiLt mice pre-EAE improved the disease course, correlated with enhanced Tregs and altered gut microbiota in Peyer's patches (Colpitts et al., 2017)

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These studies collectively contribute new insights into understanding the role of oxidative stress in IBD and potential therapeutic avenues targeting ROS-mediated pathways in the management of this condition