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In some people, these patches can appear all over the body

Fremont S, Chamigneulle B, Gerard P, Felden P, Lambert D, Gueant JL, et al

Researchers might monitor cell morphology, gene expression changes, or biochemical markers such as oxidative stress indicators and extracellular matrix components

This suggests a threshold effect related to the degree of fat tissue vascularization

Effects of Tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data