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The first double-blind trial reported initial marked improvement in 12 of 17 patients, with more favorable and lasting response in those with less severe disease

Symposium on Myelodysplastic Syndromes: Biology and Treatment, Houston, 1988

R.HoldenH.et al (2005)

The acetylated form protects the molecule during digestion for better cellular uptake

BPC-157s anti-inflammatory mechanism primarily through NO pathway modulation and reduced pro-inflammatory cytokine expression produces meaningful analgesic effects without the GI side effects associated with NSAIDs

0.5 g (0.35 mmol) of a pentadecapeptide with the sequence Gly Glu Pro Pro Pro Gly Lys Pro Ala Asp Asp Ala Gly Leu Val (BPC157) was dissolved in 10 ml water containing 29,6 mg of sodium hydrogencarbonate (0.35 mmol), sterile filtered through a 0.2 filter and dried by freeze-drying to give 0.48 g of an off-white solid